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Recent Publications (Original)
- Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates (Yang et al. EMBO J)
- Organelle landscape analysis using a multi-parametric particle-based method (Kurikawa, Honda et al. PLoS Biol.)
- Optogenetic tools for inducing organelle membrane rupture (Nagashima et al. bioRxiv)
- Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation (Shinoda et al. eLife)
- Experimental determination and mathematical modeling of standard shapes of forming autophagosomes (Sakai et al., Nat. Commun.)
- TAX1BP1 recruits ATG9 vesicles through SCAMP3 binding (Hama et al. bioRxiv)
- Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration (Shimizu et al., Hum Mol Genet.)
- Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3 (Nishimura et al., Sci Adv.)
- The pH-sensing Rim101 pathway regulates cell size in budding yeast
- Quantitative 3D correlative light and electron microscopy of organelle association during autophagy (Takahashi et al., Cell Struct Funct.)
- Ubiquitination of phosphatidylethanolamine in organellar membranes (Sakamaki et al., Mol. Cell)
- NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy（大島 et al., J. Cell Biol.）
- A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag (Yim et al., eLife)
- Evolutionary diversification of the autophagy-related ubiquitin-like conjugation systems (Zhang et al., Autophagy)
- Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins (Chino et al., EMBO Rep.)
- Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair (Yim et al., FEBS Lett)
- An exploratory text analysis of the autophagy research field (Yim, et al., Autophagy)
- NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA (Yamamoto, et al., Nat. Commun.)
- Genome-wide CRISPR screening reveals nucleotide synthesis negatively regulates autophagy (Mimura, et al., J Biol Chem)
- Organelle degradation in the lens by PLAAT phospholipases (Morishita, et al., Nature)
- Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1 (Okawa, Hama, Zhang et al., J Cell Sci)
- Autophagy is required for maturation of surfactant-containing lamellar bodies in the lung and swim bladder (Morishita, et al., Cell Rep.)
- Modeling Membrane Morphological Change during Autophagosome Formation (Sakai, et al., iScience)
- A critical role of VMP1 in lipoprotein secretion (Morishita, et al., eLife)
- Intrinsically disordered protein TEX264 mediates ER-phagy (Chino et al., Mol Cell)
- Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system (Yamamoto et al., Nat Struct Mol Biol)
- Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation (Morita et al., J Cell Biol)
- Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17 (Matsui et al., J Cell Biol)
- Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets (Tamura et al., FEBS Lett)
- Accumulation of undegraded autophagosomes by expression of dominant-negative syntaxin 17 mutants (Uematsu et al., Autophagy)
- Autophagosome formation is initiated at phosphatidylinositol synthase-enriched ER subdomains (Nishimura et al., EMBO J)
- The ATG conjugation systems are important for degradation of the inner autophagosomal membrane (Tsuboyama, Honda et al., Science)
- An autophagic flux probe that releases an internal control (Kaizuka, Morishita et al., Mol Cell)
- Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons (Yoshii, Kuma et al.)
- Ultrastructural analysis of autophagosome organization using mammalian autophagy-deficient cells (Kishi et al.)
- The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17 (Jiang et al.)
- Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids (Sahani MH et al.)
- Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids (Honda et al.)
- Differential contribution of insulin and amino acids to the mTORC1-autophagy pathway in the liver and muscle (Naito et al.)
- Deletion of Atg5 and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation (Morishita et al.)
- FIP200 regulates targeting of Atg16L1 to the isolation membrane (Nishimura)
- De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood (Nishimura)
- Proteasome-dependent activation of mTORC1 is essential for autophagy suppression and muscle remodeling following denervation (Quy)
- Atg8 localizes to the apicoplast of the human malaria parasite Plasmodium falciparum (Kitamura)
- Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets (Velikkakath, Nishimura)
- Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy (Itakura)
