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Organelle degradation in the lens by PLAAT phospholipases (Morishita, et al., Nature)
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Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1 (Okawa, Hama, Zhang et al., J Cell Sci)
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Oshima-san received the Dean’s Award from ‘Medical Scientist Training Program’ Thesis Review Committee, and Mimura-san received the 2020 SATOSHI ARIMA Memorial Fellowship
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Autophagy is required for maturation of surfactant-containing lamellar bodies in the lung and swim bladder (Morishita, et al., Cell Rep.)
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Prof. Mizushima was selected as a 2020 Clarivate Analytics Highly Cited Researcher (7th straight year)
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Modeling Membrane Morphological Change during Autophagosome Formation (Sakai, et al., iScience)
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Prof. Mizushima has been elected as an EMBO Associate Member
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Both Dr. Morishita and Oshima-san received a ‘Best Poster Award’ at the 9th International Symposium on Autophagy.
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Recent Publications (Original)
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2021/04/15
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Organelle degradation in the lens by PLAAT phospholipases (Morishita, et al., Nature)
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2021/04/01
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Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1 (Okawa, Hama, Zhang et al., J Cell Sci)
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2020/12/08
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Autophagy is required for maturation of surfactant-containing lamellar bodies in the lung and swim bladder (Morishita, et al., Cell Rep.)
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2020/09/04
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Modeling Membrane Morphological Change during Autophagosome Formation (Sakai, et al., iScience)
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2019/09/17
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A critical role of VMP1 in lipoprotein secretion (Morishita, et al., eLife)
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2019/04/19
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Intrinsically disordered protein TEX264 mediates ER-phagy (Chino et al., Mol Cell)
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2019/03/25
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Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system (Yamamoto et al., Nat Struct Mol Biol)
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2018/08/09
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Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation (Morita et al., J Cell Biol)
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2018/05/22
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Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17 (Matsui et al., J Cell Biol)
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2017/11/20
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Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets (Tamura et al., FEBS Lett)
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2017/07/27
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Accumulation of undegraded autophagosomes by expression of dominant-negative syntaxin 17 mutants (Uematsu et al., Autophagy)
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2017/05/11
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Autophagosome formation is initiated at phosphatidylinositol synthase-enriched ER subdomains (Nishimura et al., EMBO J)
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2016/11/25
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The ATG conjugation systems are important for degradation of the inner autophagosomal membrane (Tsuboyama, Honda et al., Science)
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2016/11/17
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An autophagic flux probe that releases an internal control (Kaizuka, Morishita et al., Mol Cell)
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2016/10/10
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Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons (Yoshii, Kuma et al.)
Recent Publications (Review)
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2020/10/15
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Autophagy in human diseases (*Mizushima, N., Levine, B. , N. Engl. J. Med, 2020)
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2020/08/22
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Beth Levine 1960-2020 (Simon et al. Nat Cell Biol. 2020)
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2020/08/21
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Autophagy assays for biological discovery and therapeutic development (Mizushima et al. Trends Biochem Sci. 2020)
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2020/03/02
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ER-phagy: Quality control and turnover of endoplasmic reticulum (Chino et al., Trends Cell Biol)
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2020/02/11
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Lysosome biology in autophagy (Yim et al., Cell Discov)
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2019/12/31
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The ATG conjugation systems in autophagy (Mizushima, Curr Opin Cell Biol)
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2019/10/06
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Diverse cellular roles of autophagy (Morishita et al., Annu Rev Cell Dev Biol)
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2019/09/15
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The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy (Mizushima, EMBO Rep)
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2019/02/26
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TMEM41B functions with VMP1 in autophagosome formation (Morita et al., Autophagy)
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2018/10/13
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YKT6 as a second SNARE protein of mammalian autophagosomes (Mizushima et al., Autophagy)
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2018/09/23
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A brief history of autophagy from cell biology to physiology and disease (Mizushima, Nat Cell Biol)
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2018/08/15
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Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations (Deretic et al., Autophagy)
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2018/01/22
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A dual binding receptor for ER-phagy (Mizushima, Dev Cell)