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Experimental determination and mathematical modeling of standard shapes of forming autophagosomes (Sakai et al., Nat. Commun.)
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Cantona-san won the Best Poster Award at WINGS LST general meeting
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Jing Zhang-san won the Best Student Poster Presentation Award at The 76th Annual Meeting of the Japanese Society for Cell Biology
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Dr. Eguchi won the Best Presentation Award at the 15th Autophagy Research Meeting for Young Scientists
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Prof. Mizushima have been recognized as Web of Science, Highly Cited Researchers in 2023 (10th straight year).
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Dr. Eguchi won the EMBO reports poster prize at the EMBO COB Workshop on Membrane shaping and remodeling by proteins in Kunming
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Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation (Shinoda et al. eLife)
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Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration (Shimizu et al., Hum Mol Genet.)
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Recent Publications (Original)
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2024/08/15
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Optogenetic tools for inducing organelle membrane rupture (Nagashima et al. bioRxiv)
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2024/06/05
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Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation (Shinoda et al. eLife)
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2024/01/04
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Experimental determination and mathematical modeling of standard shapes of forming autophagosomes (Sakai et al., Nat. Commun.)
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2023/09/26
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Organelle landscape analysis using a multi-parametric particle-based method (Kurikawa, Honda et al. bioRxiv)
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2023/09/12
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Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates (Yang et al. bioRxiv)
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2023/08/18
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TAX1BP1 recruits ATG9 vesicles through SCAMP3 binding (Hama et al. bioRxiv)
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2023/07/06
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Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration (Shimizu et al., Hum Mol Genet.)
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2023/06/28
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Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3 (Nishimura et al., Sci Adv.)
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2023/03/03
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The pH-sensing Rim101 pathway regulates cell size in budding yeast
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2022/12/22
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Quantitative 3D correlative light and electron microscopy of organelle association during autophagy (Takahashi et al., Cell Struct Funct.)
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2022/09/06
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Ubiquitination of phosphatidylethanolamine in organellar membranes (Sakamaki et al., Mol. Cell)
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2022/08/31
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NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy(大島 et al., J. Cell Biol.)
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2022/08/16
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A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag (Yim et al., eLife)
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2022/04/20
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Evolutionary diversification of the autophagy-related ubiquitin-like conjugation systems (Zhang et al., Autophagy)
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2022/04/20
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Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins (Chino et al., EMBO Rep.)
Recent Publications (Review)
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2023/04/28
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Ubiquitination of non-protein substrates (Sakamaki and Mizushima, Trends Cell Biol.)
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2023/01/13
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Autophagy genes in biology and disease (Yamamoto, Zhang et al., Nat Rev Genet.)
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2022/05/25
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Transient visit of STX17 (syntaxin 17) to autophagosomes (Koyama-Honda and Mizushima, Autophagy)
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2022/02/03
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Regulation of ER-derived membrane dynamics by the DedA domain-containing proteins VMP1 and TMEM41B (Hama, Morishita et al., EMBO Rep.)
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2021/07/11
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Breakthroughs and bottlenecks in autophagy research (Mizushima, et al., Trends Mol Med)
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2021/07/01
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The evolution of autophagy proteins – diversification in eukaryotes and potential ancestors in prokaryotes (Zhang, et al., J Cell Sci)
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2020/10/15
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Autophagy in human diseases (*Mizushima, N., Levine, B. , N. Engl. J. Med, 2020)
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2020/08/22
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Beth Levine 1960-2020 (Simon et al. Nat Cell Biol. 2020)
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2020/08/21
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Autophagy assays for biological discovery and therapeutic development (Mizushima et al. Trends Biochem Sci. 2020)
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2020/03/02
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ER-phagy: Quality control and turnover of endoplasmic reticulum (Chino et al., Trends Cell Biol)
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2020/02/11
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Lysosome biology in autophagy (Yim et al., Cell Discov)
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2019/12/31
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The ATG conjugation systems in autophagy (Mizushima, Curr Opin Cell Biol)
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2019/10/06
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Diverse cellular roles of autophagy (Morishita et al., Annu Rev Cell Dev Biol)
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2019/09/15
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The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy (Mizushima, EMBO Rep)
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2019/02/26
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TMEM41B functions with VMP1 in autophagosome formation (Morita et al., Autophagy)