• NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA (Yamamoto, et al., Nat. Commun.)

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  • Genome-wide CRISPR screening reveals nucleotide synthesis negatively regulates autophagy (Mimura, et al., J Biol Chem)

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  • Organelle degradation in the lens by PLAAT phospholipases (Morishita, et al., Nature)

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  • Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1 (Okawa, Hama, Zhang et al., J Cell Sci)

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  • Oshima-san received the Dean’s Award from ‘Medical Scientist Training Program’ Thesis Review Committee, and Mimura-san received the 2020 SATOSHI ARIMA Memorial Fellowship

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  • Autophagy is required for maturation of surfactant-containing lamellar bodies in the lung and swim bladder (Morishita, et al., Cell Rep.)

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  • Prof. Mizushima was selected as a 2020 Clarivate Analytics Highly Cited Researcher (7th straight year)

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  • Modeling Membrane Morphological Change during Autophagosome Formation (Sakai, et al., iScience)

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    News/Topics

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    2021/04/30
    Prof. Mizushima was awarded the Medal of Honor with Purple Ribbon
    2021/04/19
    The ERATO International Symposium will be held on Thursday, June 17, 2021
    2021/02/13
    Shimasawa-san and Suzuki-san received an Excellent Poster Abstract Award and the Best Poster Abstract Award respectively at the 2020 ‘Medical Scientist Training Program’ Retreat
    2020/12/25
    Oshima-san received the Dean’s Award from ‘Medical Scientist Training Program’ Thesis Review Committee, and Mimura-san received the 2020 SATOSHI ARIMA Memorial Fellowship
    2020/12/24
    Prof. Mizushima received “Minister of MEXT Award” at the 4th Award Ceremony for the Japan Medical Research and Development Grand Prize
    2020/11/19
    Prof. Mizushima was selected as a 2020 Clarivate Analytics Highly Cited Researcher (7th straight year)
    2020/11/01
    Prof. Mizushima received the Medical Award of the Japan Medical Association
    2020/09/16
    Yamamoto-san won Young Scientists Presentation Award of Excellence at the 93rd Annual Meeting of Japanese Biochemical Society
    2020/08/06
    Prof. Mizushima won the 61st Fujihara Award
    2020/07/08
    Prof. Mizushima has been elected as an EMBO Associate Member
    2020/06/10
    Dr. Morishita received a Young Scientist Presentation Award of Excellence at the 72nd Annual Meeting of the Japan Society for Cell Biology
    2020/02/16
    Mimura-san won an Excellent Poster Abstract Award at the 2019 ‘Medical Scientist Training Program’ Retreat
    2019/12/02
    Prof. Mizushima was selected as a 2019 Clarivate Analytics Highly Cited Researcher (6th straight year)
    2019/11/08
    Both Dr. Morishita and Oshima-san received a ‘Best Poster Award’ at the 9th International Symposium on Autophagy.
    2019/09/20
    Dr.Chino won Young Scientists Presentation Award of Excellence at at the 92nd Annual Meeting of the Japanese Biochemical Society

    Recent Publications (Original)

    and More

    2021/06/02
    NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA (Yamamoto, et al., Nat. Commun.)
    2021/05/12
    Genome-wide CRISPR screening reveals nucleotide synthesis negatively regulates autophagy (Mimura, et al., J Biol Chem)
    2021/04/15
    Organelle degradation in the lens by PLAAT phospholipases (Morishita, et al., Nature)
    2021/04/01
    Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1 (Okawa, Hama, Zhang et al., J Cell Sci)
    2020/12/08
    Autophagy is required for maturation of surfactant-containing lamellar bodies in the lung and swim bladder (Morishita, et al., Cell Rep.)
    2020/09/04
    Modeling Membrane Morphological Change during Autophagosome Formation (Sakai, et al., iScience)
    2019/09/17
    A critical role of VMP1 in lipoprotein secretion (Morishita, et al., eLife)
    2019/04/19
    Intrinsically disordered protein TEX264 mediates ER-phagy (Chino et al., Mol Cell)
    2019/03/25
    Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system (Yamamoto et al., Nat Struct Mol Biol)
    2018/08/09
    Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation (Morita et al., J Cell Biol)
    2018/05/22
    Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17 (Matsui et al., J Cell Biol)
    2017/11/20
    Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets (Tamura et al., FEBS Lett)
    2017/07/27
    Accumulation of undegraded autophagosomes by expression of dominant-negative syntaxin 17 mutants (Uematsu et al., Autophagy)
    2017/05/11
    Autophagosome formation is initiated at phosphatidylinositol synthase-enriched ER subdomains (Nishimura et al., EMBO J)
    2016/11/25
    The ATG conjugation systems are important for degradation of the inner autophagosomal membrane (Tsuboyama, Honda et al., Science)

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    Mizushima Lab