• Experimental determination and mathematical modeling of standard shapes of forming autophagosomes (Sakai et al., Nat. Commun.)

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  • Dr. Eguchi won the Best Presentation Award at the 15th Autophagy Research Meeting for Young Scientists

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  • Prof. Mizushima have been recognized as Web of Science, Highly Cited Researchers in 2023 (10th straight year).

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  • Dr. Eguchi won the EMBO reports poster prize at the EMBO COB Workshop on Membrane shaping and remodeling by proteins in Kunming

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  • Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration (Shimizu et al., Hum Mol Genet.)

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  • Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3 (Nishimura et al., Sci Adv.)

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  • The pH-sensing Rim101 pathway regulates cell size in budding yeast

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  • NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy(大島 et al., J. Cell Biol.)

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    News/Topics

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    2024/02/16
    Yamaguchi-san received the Best Poster Abstract Award at the 2023 ‘Medical Scientist Training Program’ Retreat
    2023/12/24
    Kanda-san won the MBSJ2023 Best Science Pitch Award at the 46th Annual Meeting of the Molecular Biology Society of Japan
    2023/12/01
    Dr. Eguchi won the Best Presentation Award at the 15th Autophagy Research Meeting for Young Scientists
    2023/11/20
    Prof. Mizushima have been recognized as Web of Science, Highly Cited Researchers in 2023 (10th straight year).
    2023/11/20
    Kanda-san, Okawa-san and Nagashima-san won Young Scientists Presentation Award of Excellence at the 96rd Annual Meeting of Japanese Biochemical Society
    2023/11/20
    Dr. Eguchi won the EMBO reports poster prize at the EMBO COB Workshop on Membrane shaping and remodeling by proteins in Kunming
    2023/06/23
    Prof. Mizushima awarded inaugural Beth Levine, M.D. Prize in Autophagy Research
    2023/06/19
    Okawa-san won an Excellent Poster Award at the 22th BioUT (Life Science Symposium at the University of Tokyo)
    2023/02/15
    Nagashima-san and Suzuki-san received an Excellent Poster Abstract Award and the Best Poster Abstract Award respectively at the 2022 ‘Medical Scientist Training Program’ Retreat
    2022/12/16
    Shimasawa-san received the 2020 SATOSHI ARIMA Memorial Fellowship
    2022/11/16
    Prof. Mizushima have been recognized as Web of Science, Highly Cited Researchers in 2022 (9th straight year).
    2022/02/14
    Shimasawa-san received an Excellent Poster Abstract Award at the 2021 ‘Medical Scientist Training Program’ Retreat
    2022/02/12
    Dr. Chino received Inoue Research Award for Young Scientists.
    2021/11/17
    Prof. Mizushima was selected as a 2021 Clarivate Analytics Highly Cited Researcher (8th straight year)
    2021/09/10
    The ERATO Symposium was held on Thursday, November 11, 2021

    Recent Publications (Original)

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    2024/01/04
    Experimental determination and mathematical modeling of standard shapes of forming autophagosomes (Sakai et al., Nat. Commun.)
    2023/09/26
    Organelle landscape analysis using a multi-parametric particle-based method (Kurikawa, Honda et al. bioRxiv)
    2023/09/12
    Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation (Shinoda et al. bioRxiv)
    2023/09/12
    Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates (Yang et al. bioRxiv)
    2023/08/18
    TAX1BP1 recruits ATG9 vesicles through SCAMP3 binding (Hama et al. bioRxiv)
    2023/07/06
    Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration (Shimizu et al., Hum Mol Genet.)
    2023/06/28
    Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3 (Nishimura et al., Sci Adv.)
    2023/03/03
    The pH-sensing Rim101 pathway regulates cell size in budding yeast
    2022/12/22
    Quantitative 3D correlative light and electron microscopy of organelle association during autophagy (Takahashi et al., Cell Struct Funct.)
    2022/09/06
    Ubiquitination of phosphatidylethanolamine in organellar membranes (Sakamaki et al., Mol. Cell)
    2022/08/31
    NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy(大島 et al., J. Cell Biol.)
    2022/08/16
    A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag (Yim et al., eLife)
    2022/04/20
    Evolutionary diversification of the autophagy-related ubiquitin-like conjugation systems (Zhang et al., Autophagy)
    2022/04/20
    Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins (Chino et al., EMBO Rep.)
    2022/04/20
    Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair (Yim et al., FEBS Lett)

    Recent Publications (Review)

    and More

    2023/04/28
    Ubiquitination of non-protein substrates (Sakamaki and Mizushima, Trends Cell Biol.)
    2023/01/13
    Autophagy genes in biology and disease (Yamamoto, Zhang et al., Nat Rev Genet.)
    2022/05/25
    Transient visit of STX17 (syntaxin 17) to autophagosomes (Koyama-Honda and Mizushima, Autophagy)
    2022/02/03
    Regulation of ER-derived membrane dynamics by the DedA domain-containing proteins VMP1 and TMEM41B (Hama, Morishita et al., EMBO Rep.)
    2021/07/11
    Breakthroughs and bottlenecks in autophagy research (Mizushima, et al., Trends Mol Med)
    2021/07/01
    The evolution of autophagy proteins – diversification in eukaryotes and potential ancestors in prokaryotes (Zhang, et al., J Cell Sci)
    2020/10/15
    Autophagy in human diseases (*Mizushima, N., Levine, B. , N. Engl. J. Med, 2020)
    2020/08/22
    Beth Levine 1960-2020 (Simon et al. Nat Cell Biol. 2020)
    2020/08/21
    Autophagy assays for biological discovery and therapeutic development (Mizushima et al. Trends Biochem Sci. 2020)
    2020/03/02
    ER-phagy: Quality control and turnover of endoplasmic reticulum (Chino et al., Trends Cell Biol)
    2020/02/11
    Lysosome biology in autophagy (Yim et al., Cell Discov)
    2019/12/31
    The ATG conjugation systems in autophagy (Mizushima, Curr Opin Cell Biol)
    2019/10/06
    Diverse cellular roles of autophagy (Morishita et al., Annu Rev Cell Dev Biol)
    2019/09/15
    The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy (Mizushima, EMBO Rep)
    2019/02/26
    TMEM41B functions with VMP1 in autophagosome formation (Morita et al., Autophagy)

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