• Evolutionary diversification of the autophagy-related ubiquitin-like conjugation systems (Zhang et al., Autophagy)

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  • Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair (Yim et al., FEBS Lett)

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  • An exploratory text analysis of the autophagy research field (Yim, et al., Autophagy)

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  • NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA (Yamamoto, et al., Nat. Commun.)

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  • Genome-wide CRISPR screening reveals nucleotide synthesis negatively regulates autophagy (Mimura, et al., J Biol Chem)

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  • Organelle degradation in the lens by PLAAT phospholipases (Morishita, et al., Nature)

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  • Prof. Mizushima was selected as a 2021 Clarivate Analytics Highly Cited Researcher (8th straight year)

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  • Modeling Membrane Morphological Change during Autophagosome Formation (Sakai, et al., iScience)

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    News/Topics

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    2022/02/14
    Shimasawa-san received an Excellent Poster Abstract Award at the 2021 ‘Medical Scientist Training Program’ Retreat
    2022/02/12
    Dr. Chino received Inoue Research Award for Young Scientists.
    2021/11/17
    Prof. Mizushima was selected as a 2021 Clarivate Analytics Highly Cited Researcher (8th straight year)
    2021/09/10
    The ERATO Symposium was held on Thursday, November 11, 2021
    2021/06/17
    The ERATO International Symposium was held on Thursday, June 17, 2021
    2021/04/30
    Prof. Mizushima was awarded the Medal of Honor with Purple Ribbon
    2021/02/13
    Shimasawa-san and Suzuki-san received an Excellent Poster Abstract Award and the Best Poster Abstract Award respectively at the 2020 ‘Medical Scientist Training Program’ Retreat
    2020/12/25
    Oshima-san received the Dean’s Award from ‘Medical Scientist Training Program’ Thesis Review Committee, and Mimura-san received the 2020 SATOSHI ARIMA Memorial Fellowship
    2020/12/24
    Prof. Mizushima received “Minister of MEXT Award” at the 4th Award Ceremony for the Japan Medical Research and Development Grand Prize
    2020/11/19
    Prof. Mizushima was selected as a 2020 Clarivate Analytics Highly Cited Researcher (7th straight year)
    2020/11/01
    Prof. Mizushima received the Medical Award of the Japan Medical Association
    2020/09/16
    Yamamoto-san won Young Scientists Presentation Award of Excellence at the 93rd Annual Meeting of Japanese Biochemical Society
    2020/08/06
    Prof. Mizushima won the 61st Fujihara Award
    2020/07/08
    Prof. Mizushima has been elected as an EMBO Associate Member
    2020/06/10
    Dr. Morishita received a Young Scientist Presentation Award of Excellence at the 72nd Annual Meeting of the Japan Society for Cell Biology

    Recent Publications (Original)

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    2022/04/20
    Evolutionary diversification of the autophagy-related ubiquitin-like conjugation systems (Zhang et al., Autophagy)
    2022/04/20
    Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins (Chino et al., EMBO Rep.)
    2022/04/20
    Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair (Yim et al., FEBS Lett)
    2021/11/23
    An exploratory text analysis of the autophagy research field (Yim, et al., Autophagy)
    2021/06/02
    NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA (Yamamoto, et al., Nat. Commun.)
    2021/05/12
    Genome-wide CRISPR screening reveals nucleotide synthesis negatively regulates autophagy (Mimura, et al., J Biol Chem)
    2021/04/15
    Organelle degradation in the lens by PLAAT phospholipases (Morishita, et al., Nature)
    2021/04/01
    Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1 (Okawa, Hama, Zhang et al., J Cell Sci)
    2020/12/08
    Autophagy is required for maturation of surfactant-containing lamellar bodies in the lung and swim bladder (Morishita, et al., Cell Rep.)
    2020/09/04
    Modeling Membrane Morphological Change during Autophagosome Formation (Sakai, et al., iScience)
    2019/09/17
    A critical role of VMP1 in lipoprotein secretion (Morishita, et al., eLife)
    2019/04/19
    Intrinsically disordered protein TEX264 mediates ER-phagy (Chino et al., Mol Cell)
    2019/03/25
    Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system (Yamamoto et al., Nat Struct Mol Biol)
    2018/08/09
    Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation (Morita et al., J Cell Biol)
    2018/05/22
    Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17 (Matsui et al., J Cell Biol)

    Recent Publications (Review)

    and More

    2022/02/03
    Regulation of ER-derived membrane dynamics by the DedA domain-containing proteins VMP1 and TMEM41B (Hama, Morishita et al., EMBO Rep.)
    2021/07/11
    Breakthroughs and bottlenecks in autophagy research (Mizushima, et al., Trends Mol Med)
    2021/07/01
    The evolution of autophagy proteins – diversification in eukaryotes and potential ancestors in prokaryotes (Zhang, et al., J Cell Sci)
    2020/10/15
    Autophagy in human diseases (*Mizushima, N., Levine, B. , N. Engl. J. Med, 2020)
    2020/08/22
    Beth Levine 1960-2020 (Simon et al. Nat Cell Biol. 2020)
    2020/08/21
    Autophagy assays for biological discovery and therapeutic development (Mizushima et al. Trends Biochem Sci. 2020)
    2020/03/02
    ER-phagy: Quality control and turnover of endoplasmic reticulum (Chino et al., Trends Cell Biol)
    2020/02/11
    Lysosome biology in autophagy (Yim et al., Cell Discov)
    2019/12/31
    The ATG conjugation systems in autophagy (Mizushima, Curr Opin Cell Biol)
    2019/10/06
    Diverse cellular roles of autophagy (Morishita et al., Annu Rev Cell Dev Biol)
    2019/09/15
    The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy (Mizushima, EMBO Rep)
    2019/02/26
    TMEM41B functions with VMP1 in autophagosome formation (Morita et al., Autophagy)
    2018/10/13
    YKT6 as a second SNARE protein of mammalian autophagosomes (Mizushima et al., Autophagy)
    2018/09/23
    A brief history of autophagy from cell biology to physiology and disease (Mizushima, Nat Cell Biol)
    2018/08/15
    Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations (Deretic et al., Autophagy)

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