News/Topics
- 2025/06/20
- Kita-san won an Poster Award at the BIO UT 2025
- 2025/02/19
- Kobatake-san received the Excellent Poster Award at the 2024 ‘Medical Scientist Training Program’ Retreat
- 2025/02/06
- Recruitment of graduate students
- 2024/11/20
- Prof. Mizushima has been recognized as Web of Science, Highly Cited Researchers in 2024 (11th consecutive year).
- 2024/10/18
- Dr. Hayashi won an Excellent Poster Award at the 16th Autophagy Research Meeting for Young Scientists
- 2024/07/19
- Jing Zhang-san won the Best Student Poster Presentation Award at The 76th Annual Meeting of the Japanese Society for Cell Biology
- 2024/07/06
- Cantona-san won the Best Poster Award at WINGS LST general meeting
- 2024/02/16
- Yamaguchi-san received the Best Poster Abstract Award at the 2023 ‘Medical Scientist Training Program’ Retreat
- 2023/12/24
- Kanda-san won the MBSJ2023 Best Science Pitch Award at the 46th Annual Meeting of the Molecular Biology Society of Japan
- 2023/12/01
- Dr. Eguchi won the Best Presentation Award at the 15th Autophagy Research Meeting for Young Scientists
- 2023/11/20
- Prof. Mizushima have been recognized as Web of Science, Highly Cited Researchers in 2023 (10th straight year).
- 2023/11/20
- Kanda-san, Okawa-san and Nagashima-san won Young Scientists Presentation Award of Excellence at the 96rd Annual Meeting of Japanese Biochemical Society
- 2023/11/20
- Dr. Eguchi won the EMBO reports poster prize at the EMBO COB Workshop on Membrane shaping and remodeling by proteins in Kunming
- 2023/06/23
- Prof. Mizushima awarded inaugural Beth Levine, M.D. Prize in Autophagy Research
- 2023/06/19
- Okawa-san won an Excellent Poster Award at the 22th BioUT (Life Science Symposium at the University of Tokyo)
Recent Publications (Original)
- 2025/09/17
- Evolutionary diversification of the autophagy initiation complex: reduced Atg101 dependency and changes in Atg9 binding to Atg13
- 2025/03/18
- Optogenetic tools for inducing organelle membrane rupture (Nagashima et al. J Biol Chem.)
- 2024/10/25
- Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates (Yang et al. EMBO J)
- 2024/09/17
- Organelle landscape analysis using a multi-parametric particle-based method (Kurikawa, Honda et al. PLoS Biol.)
- 2024/06/05
- Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation (Shinoda et al. eLife)
- 2024/01/04
- Experimental determination and mathematical modeling of standard shapes of forming autophagosomes (Sakai et al., Nat. Commun.)
- 2023/08/18
- TAX1BP1 recruits ATG9 vesicles through SCAMP3 binding (Hama et al. bioRxiv)
- 2023/07/06
- Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration (Shimizu et al., Hum Mol Genet.)
- 2023/06/28
- Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3 (Nishimura et al., Sci Adv.)
- 2023/03/03
- The pH-sensing Rim101 pathway regulates cell size in budding yeast
- 2022/12/22
- Quantitative 3D correlative light and electron microscopy of organelle association during autophagy (Takahashi et al., Cell Struct Funct.)
- 2022/09/06
- Ubiquitination of phosphatidylethanolamine in organellar membranes (Sakamaki et al., Mol. Cell)
- 2022/08/31
- NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy（大島 et al., J. Cell Biol.）
- 2022/08/16
- A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag (Yim et al., eLife)
- 2022/04/20
- Evolutionary diversification of the autophagy-related ubiquitin-like conjugation systems (Zhang et al., Autophagy)
Recent Publications (Review)
- 2025/01/29
- Autophagic flux measurement: cargo degradation versus generation of degradation products (Mizushima, Curr Opin Cell Biol.)
- 2023/04/28
- Ubiquitination of non-protein substrates (Sakamaki and Mizushima, Trends Cell Biol.)
- 2023/01/13
- Autophagy genes in biology and disease (Yamamoto, Zhang et al., Nat Rev Genet.)
- 2022/05/25
- Transient visit of STX17 (syntaxin 17) to autophagosomes (Koyama-Honda and Mizushima, Autophagy)
- 2022/02/03
- Regulation of ER-derived membrane dynamics by the DedA domain-containing proteins VMP1 and TMEM41B (Hama, Morishita et al., EMBO Rep.)
- 2021/07/11
- Breakthroughs and bottlenecks in autophagy research (Mizushima, et al., Trends Mol Med)
- 2021/07/01
- The evolution of autophagy proteins – diversification in eukaryotes and potential ancestors in prokaryotes (Zhang, et al., J Cell Sci)
- 2020/10/15
- Autophagy in human diseases (*Mizushima, N., Levine, B. , N. Engl. J. Med, 2020)
- 2020/08/22
- Beth Levine 1960-2020 (Simon et al. Nat Cell Biol. 2020)
- 2020/08/21
- Autophagy assays for biological discovery and therapeutic development (Mizushima et al. Trends Biochem Sci. 2020)
- 2020/03/02
- ER-phagy: Quality control and turnover of endoplasmic reticulum (Chino et al., Trends Cell Biol)
- 2020/02/11
- Lysosome biology in autophagy (Yim et al., Cell Discov)
- 2019/12/31
- The ATG conjugation systems in autophagy (Mizushima, Curr Opin Cell Biol)
- 2019/10/06
- Diverse cellular roles of autophagy (Morishita et al., Annu Rev Cell Dev Biol)
- 2019/09/15
- The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy (Mizushima, EMBO Rep)
