発表論文
Review
2023年
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Hayashi Yamamoto, Sidi Zhang & Noboru Mizushima
Autophagy genes in biology and disease
Nat Rev Genet. 2023 Jan 12
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2022年
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Noboru Mizushima
SnapShot: Organelle degradation
Mol Cell. 2022 Apr 21;82(8):1604-1604.e1.
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Yutaro Hama*, Hideaki Morishita*, Noboru Mizushima (* equally contributed)
Regulation of ER-derived membrane dynamics by the DedA domain-containing proteins VMP1 and TMEM41B
EMBO Rep. 2022 Jan 19;e53894.
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2021年
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Noboru Mizushima, Eileen White, David C Rubinsztein
Breakthroughs and bottlenecks in autophagy research
Trends Mol Med 2021 Jul 11;S1471-4914(21)00179-9
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Hideaki Morishita, Tomoya Eguchi, Noboru Mizushima
A new insight into the lens: cytosolic PLAAT phospholipases degrade organelles to make the lens transparent
Autophagy 2021 Jul 7;1-3.
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Sidi Zhang, Yutaro Hama, Noboru Mizushima
The evolution of autophagy proteins – diversification in eukaryotes and potential ancestors in prokaryotes
J Cell Sci 2021 Jul 1;134(13):jcs233742
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Yutaro Hama, Sidi Zhang, Noboru Mizushima
ZZ domains keep cytosol to vacuole delivery whiZZing along
EMBO J 2021 Jun 25;e108777.
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Hideaki Morishita, Yuki Kanda, Noboru Mizushima
No air without autophagy: autophagy is important for lung and swim bladder inflatio
Autophagy 2021 Apr;17(4):1040-1041
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Sebastian W Schultz, Jaime Agudo-Canalejo, Haruka Chino, Simona M Migliano, Chieko Saito, Ikuko Koyama-Honda, Harald Stenmark, Andreas Brech, Noboru Mizushima, Roland L Knorr, Alexander I May
Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
Autophagy 2021 Apr;17(4):1046-1048.
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Willa Wen-You Yim, Noboru Mizushima
Autophagosome maturation stymied by SARS-CoV-2
Dev Cell 2021 Feb 22;56(4):400-402
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Klionsky DJ, Mizushima N, et al.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Autophagy 2021 Jan;17(1):1-382
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2020年
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*Mizushima N, Levine B
Autophagy in human diseases
N. Engl. J. Med 383:1564-1576 (2020)
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Simon A. K., Mizushima N.
Beth Levine 1960-2020
Nat Cell Biol 2020 Aug;22(8):909-910.
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Mizushima N., Murphy L. O.
Autophagy assays for biological discovery and therapeutic development
Trends Biochem Sci 2020 Aug 21;S0968-0004(20)30191-2
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Chino, H., Mizushima, N.
ER-Phagy: Quality Control and Turnover of Endoplasmic Reticulum
Trends Cell Biol 2020 May;30(5):384-398.
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Yim, W.W., Mizushima, N.
Lysosome biology in autophagy
Cell Discov 2020 Feb 11;6:6
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2019年
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Mizushima, N.
The ATG conjugation systems in autophagy
Curr Opin Cell Biol 2020 Apr;63:1-10
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Mizushima N.
The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy
EMBO Rep. 2019 15:e49104
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Morishita H., Mizushima N.
Diverse cellular roles of autophagy
Annu. Rev. Cell Dev. Biol. 2019 Epub ahead of print
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Morita K, Hama Y, Mizushima N.
TMEM41B functions with VMP1 in autophagosome formation
Autophagy 2019 May;15(5):922-923
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2018年
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Mizushima N, Matsui T, Yamamoto H.
YKT6 as a second SNARE protein of mammalian autophagosomes
Autophagy 2019 Jan;15(1):176-177
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Deretic V, , MIzushima N, et al.
Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations
Autophagy 2018;14(6):925-929
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Mizushima N.
A brief history of autophagy from cell biology to physiology and disease.
Nat Cell Biol 2018 May;20(5):521-527
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Mizushima N.
A Dual Binding Receptor for ER-phagy
Dev Cell 2018 Jan 22;44(2):133-135
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2017年
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Knorr RL, Mizushima N, Dimova R.
Fusion and scission of membranes: Ubiquitous topological transformations in cells
Traffic 2017 Nov;18(11):758-761
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Yoshii SR, Mizushima N.
Monitoring and Measuring Autophagy
Int J Mol Sci 2017 Aug 28;18(9). pii: E1865
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Kuma A, Komatsu M, Mizushima N.
Autophagy-monitoring and autophagy-deficient mice.
Autophagy 2017 Oct 3;13(10):1795-1796
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Nishimura T, Mizushima N.
The ULK complex initiates autophagosome formation at phosphatidylinositol synthase-enriched ER subdomains.
Autophagy 2017 Oct 3;13(10):1795-1796
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Galluzzi L, Mizushima N, et al.
Molecular definitions of autophagy and related processes
EMBO J 2017 Jul 3;36(13):1811-1836
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Koyama-Honda I, Tsuboyama K, Mizushima N.
ATG conjugation-dependent degradation of the inner autophagosomal membrane is a key step for autophagosome maturation
Autophagy 2017 Jul 3;13(7):1252-1253.
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Mizushima N.
The exponential growth of autophagy-related research: from the humble yeast to the Nobel Prize
FEBS Lett 2017 Mar;591(5):681-689
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Yoshii SR, Kuma A, Mizushima N.
Transgenic rescue of Atg5-null mice from neonatal lethality with neuron-specific expression of ATG5: Systemic analysis of adult Atg5-deficient mice
Autophagy 2017 Apr 3;13(4):763-764
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Morishita H, Kaizuka T, Hama Y, Mizushima N.
A new probe to measure autophagic flux in vitro and in vivo
Autophagy 2017 Apr 3;13(4):757-758
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2016年
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Klionsky DJ, Mizushima N, et al.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy 2016 Jan 2;12(1):1-222
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Noda NN, Mizushima N.
Atg101: Not Just an Accessory Subunit in the Autophagy-initiation Complex
Cell Struct Funct 2016;41(1):13-20
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2015年
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Suzuki H, Kaizuka T, Mizushima N, Noda NN.
Open and closed HORMAs regulate autophagy initiation
Autophagy 2015 Nov 2;11(11):2123-2124
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Mizushima N.
Nbr1, a Receptor for ESCRT-Dependent Endosomal Microautophagy in Fission Yeast
Mol Cell 2015 Sep 17;59(6):887-9
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Morishita H, Mizushima N.
Autophagy in the lens
Exp Eye Res 2016 Mar;144:22-8
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Yoshii SR, Mizushima N.
Autophagy machinery in the context of mammalian mitophagy
Biochim Biophys Acta 2015 Oct;1853(10 Pt B):2797-801
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Galluzzi L, Mizushima N, et al.
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Cell Death Differ 2015 Jan;22(1):58-73
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2014年
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Mizushima N.
Sugar modification inhibits autophagosome-lysosome fusion
Nat Cell Biol 2014 Dec;16(12):1132-3
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Jiang P, Mizushima N.
LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells
Methods 2015 Mar;75:13-8
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Mizushima N, Sahani MH.
ATG8 localization in apicomplexan parasites: apicoplast and more?
Autophagy 2014 Sep;10(9):1487-94
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2013年
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Shen HM, Mizushima N.
At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy
Trends Biochem Sci 2014 Feb;39(2):61-71
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Jiang P, Mizushima N.
Autophagy and human diseases
Cell Res 2014 Jan;24(1):69-79
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Itakura E, Mizushima N.
Syntaxin 17: the autophagosomal SNARE
Autophagy 2013 Jun 1;9(6):917-9.
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2012年
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Klionsky DJ, Mizushima N, et al.
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy 2012 Apr;8(4):445-544
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