Jun-ichi Sakamaki & Noboru Mizushima
Ubiquitination of non-protein substrates
Hayashi Yamamoto, Sidi Zhang & Noboru Mizushima
Autophagy genes in biology and disease
Nat Rev Genet. 2023 Jan 12


Ikuko Koyama-Honda & Noboru Mizushima
Transient visit of STX17 (syntaxin 17) to autophagosomes
Autophagy 2022 May 25
Noboru Mizushima
SnapShot: Organelle degradation
Mol Cell. 2022 Apr 21;82(8):1604-1604.e1.
Yutaro Hama*, Hideaki Morishita*, Noboru Mizushima (* equally contributed)
Regulation of ER-derived membrane dynamics by the DedA domain-containing proteins VMP1 and TMEM41B
EMBO Rep. 2022 Jan 19;e53894.


Noboru Mizushima, Eileen White, David C Rubinsztein
Breakthroughs and bottlenecks in autophagy research
Trends Mol Med 2021 Jul 11;S1471-4914(21)00179-9
Hideaki Morishita, Tomoya Eguchi, Noboru Mizushima
A new insight into the lens: cytosolic PLAAT phospholipases degrade organelles to make the lens transparent
Autophagy 2021 Jul 7;1-3.
Sidi Zhang, Yutaro Hama, Noboru Mizushima
The evolution of autophagy proteins – diversification in eukaryotes and potential ancestors in prokaryotes
J Cell Sci 2021 Jul 1;134(13):jcs233742
Yutaro Hama, Sidi Zhang, Noboru Mizushima
ZZ domains keep cytosol to vacuole delivery whiZZing along
EMBO J 2021 Jun 25;e108777.
Hideaki Morishita, Yuki Kanda, Noboru Mizushima
No air without autophagy: autophagy is important for lung and swim bladder inflatio
Autophagy 2021 Apr;17(4):1040-1041
Sebastian W Schultz, Jaime Agudo-Canalejo, Haruka Chino, Simona M Migliano, Chieko Saito, Ikuko Koyama-Honda, Harald Stenmark, Andreas Brech, Noboru Mizushima, Roland L Knorr, Alexander I May
Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
Autophagy 2021 Apr;17(4):1046-1048.
Willa Wen-You Yim, Noboru Mizushima
Autophagosome maturation stymied by SARS-CoV-2
Dev Cell 2021 Feb 22;56(4):400-402
Klionsky DJ, Mizushima N, et al.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Autophagy 2021 Jan;17(1):1-382


*Mizushima N, Levine B
Autophagy in human diseases
N. Engl. J. Med 383:1564-1576 (2020)
Simon A. K., Mizushima N.
Beth Levine 1960-2020
Nat Cell Biol 2020 Aug;22(8):909-910.
Mizushima N., Murphy L. O.
Autophagy assays for biological discovery and therapeutic development
Trends Biochem Sci 2020 Aug 21;S0968-0004(20)30191-2
Chino, H., Mizushima, N.
ER-Phagy: Quality Control and Turnover of Endoplasmic Reticulum
Trends Cell Biol 2020 May;30(5):384-398.
Yim, W.W., Mizushima, N.
Lysosome biology in autophagy
Cell Discov 2020 Feb 11;6:6


Mizushima, N.
The ATG conjugation systems in autophagy
Curr Opin Cell Biol 2020 Apr;63:1-10
Mizushima N.
The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy
EMBO Rep. 2019 15:e49104
Morishita H., Mizushima N.
Diverse cellular roles of autophagy
Annu. Rev. Cell Dev. Biol. 2019 Epub ahead of print
Morita K, Hama Y, Mizushima N.
TMEM41B functions with VMP1 in autophagosome formation
Autophagy 2019 May;15(5):922-923


Mizushima N, Matsui T, Yamamoto H.
YKT6 as a second SNARE protein of mammalian autophagosomes
Autophagy 2019 Jan;15(1):176-177
Deretic V, , MIzushima N, et al.
Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations
Autophagy 2018;14(6):925-929
Mizushima N.
A brief history of autophagy from cell biology to physiology and disease.
Nat Cell Biol 2018 May;20(5):521-527
Mizushima N.
A Dual Binding Receptor for ER-phagy
Dev Cell 2018 Jan 22;44(2):133-135


Knorr RL, Mizushima N, Dimova R.
Fusion and scission of membranes: Ubiquitous topological transformations in cells
Traffic 2017 Nov;18(11):758-761
Yoshii SR, Mizushima N.
Monitoring and Measuring Autophagy
Int J Mol Sci 2017 Aug 28;18(9). pii: E1865
Kuma A, Komatsu M, Mizushima N.
Autophagy-monitoring and autophagy-deficient mice.
Autophagy 2017 Oct 3;13(10):1795-1796
Nishimura T, Mizushima N.
The ULK complex initiates autophagosome formation at phosphatidylinositol synthase-enriched ER subdomains.
Autophagy 2017 Oct 3;13(10):1795-1796
Galluzzi L, Mizushima N, et al.
Molecular definitions of autophagy and related processes
EMBO J 2017 Jul 3;36(13):1811-1836
Koyama-Honda I, Tsuboyama K, Mizushima N.
ATG conjugation-dependent degradation of the inner autophagosomal membrane is a key step for autophagosome maturation
Autophagy 2017 Jul 3;13(7):1252-1253.
Mizushima N.
The exponential growth of autophagy-related research: from the humble yeast to the Nobel Prize
FEBS Lett 2017 Mar;591(5):681-689
Yoshii SR, Kuma A, Mizushima N.
Transgenic rescue of Atg5-null mice from neonatal lethality with neuron-specific expression of ATG5: Systemic analysis of adult Atg5-deficient mice
Autophagy 2017 Apr 3;13(4):763-764
Morishita H, Kaizuka T, Hama Y, Mizushima N.
A new probe to measure autophagic flux in vitro and in vivo
Autophagy 2017 Apr 3;13(4):757-758


Klionsky DJ, Mizushima N, et al.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy 2016 Jan 2;12(1):1-222
Noda NN, Mizushima N.
Atg101: Not Just an Accessory Subunit in the Autophagy-initiation Complex
Cell Struct Funct 2016;41(1):13-20


Suzuki H, Kaizuka T, Mizushima N, Noda NN.
Open and closed HORMAs regulate autophagy initiation
Autophagy 2015 Nov 2;11(11):2123-2124
Mizushima N.
Nbr1, a Receptor for ESCRT-Dependent Endosomal Microautophagy in Fission Yeast
Mol Cell 2015 Sep 17;59(6):887-9
Morishita H, Mizushima N.
Autophagy in the lens
Exp Eye Res 2016 Mar;144:22-8
Yoshii SR, Mizushima N.
Autophagy machinery in the context of mammalian mitophagy
Biochim Biophys Acta 2015 Oct;1853(10 Pt B):2797-801
Galluzzi L, Mizushima N, et al.
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Cell Death Differ 2015 Jan;22(1):58-73


Mizushima N.
Sugar modification inhibits autophagosome-lysosome fusion
Nat Cell Biol 2014 Dec;16(12):1132-3
Jiang P, Mizushima N.
LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells
Methods 2015 Mar;75:13-8
Mizushima N, Sahani MH.
ATG8 localization in apicomplexan parasites: apicoplast and more?
Autophagy 2014 Sep;10(9):1487-94


Shen HM, Mizushima N.
At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy
Trends Biochem Sci 2014 Feb;39(2):61-71
Jiang P, Mizushima N.
Autophagy and human diseases
Cell Res 2014 Jan;24(1):69-79
Itakura E, Mizushima N.
Syntaxin 17: the autophagosomal SNARE.
Autophagy 2013 Jun 1;9(6):917-9.


Klionsky DJ, Mizushima N, et al.
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy 2012 Apr;8(4):445-544

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