People
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Project Researcher
Kamil Sołtysik
Profile
Education:
2014: Medical University of Silesia, Poland (M.D.)
2019: Nagoya University Graduate School of Medicine, Japan (Ph.D.)
Research Positions:
2019- Postdoctoral Fellow, Graduate School and Faculty of Medicine, The University of Tokyo, Japan
Results
Original Papers Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner Sołtysik K, Ohsaki Y, Tatematsu T, Cheng J, Maeda A, Morita S, Fujimoto T. J Cell Biol 220:e202005026. 2021. Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis Sołtysik K, Ohsaki Y, Tatematsu T, Cheng J, Fujimoto T. Nat Commun 10:473 2019. Late-Onset Puberty Induction by Transdermal Estrogen in Turner Syndrome Girls-A Longitudinal Study Gawlik A, Hankus M, Szeliga K, Antosz A, Gawlik T, Soltysik K, Drosdzol-Cop A, Wilk K, Kudela G,Koszutski T, Malecka-Tendera E. Front Endocrinol (Lausanne) 9:23 2018. Prediction of Spontaneous Puberty in Turner Syndrome Based on Mid-Childhood Gonadotropin Concentrations, Karyotype, and Ovary Visualization: A Longitudinal Study Hankus M, Soltysik K, Szeliga K, Antosz A, Drosdzol-Cop A, Wilk K, Zachurzok A, Malecka-Tendera E, Gawlik A. Horm Res Paediatr 89:90-97 2017. -
Project Researcher
Yoshitaka Kurikawa
Profile
2013年 東京大学医学部医学科卒業
2017年 東京大学大学院医学系研究科修了（医学博士）
2018年- 東京大学大学院医学系研究科特任研究員Results
Saori R. Yoshii*, Akiko Kuma* (*equally contributed), Takumi Akashi, Taichi Hara, Atsushi Yamamoto, Yoshitaka Kurikawa, Eisuke Itakura, Satoshi Tsukamoto, Hiroshi Shitara, Yoshinobu Eishi, Noboru Mizushima. Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons. Dev Cell 2016 Oct 10;39(1):116-130 Yanagida K, Kurikawa Y, Shimizu T, Ishii S. Current progress in non-Edg family LPA receptor research. Biochim Biophys Acta. 2013 Jan;1831(1):33-41. Epub 2012 Aug 11. Pang Y, Yamamoto H, Sakamoto H, Oku M, Mutungi JK, Sahani MH, Kurikawa Y, Kita K, Noda NN, Sakai Y, Jia H, Mizushima N. Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system. Nat Struct Mol Biol. 2019 Apr;26(4):289-296 Tsukasaki M, Huynh NC, Okamoto K, Muro R, Terashima A, Kurikawa Y, Komatsu N, Pluemsakunthai W, Nitta T, Abe T, Kiyonari H, Okamura T, Sakai M, Matsukawa T, Matsumoto M, Kobayashi Y, Penninger JM, Takayanagi H. Stepwise cell fate decision pathways during osteoclastogenesis at single-cell resolution. Nat Metab. 2020 Dec;2(12):1382-1390 Introductory Article
栗川義峻、水島昇 mTOR複合体・AMPKとオートファジー The Lipid 26(1), 40-47, 2015 栗川義峻、水島昇 オートファジー・リソソームの活性制御と飢餓応答 細胞 (2019) 栗川義峻 オートファジー研究におけるプロテオミクス 医学のあゆみ 272巻9号 (2020) -
Project Researcher
Sidi Zhang
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Project Researcher
Haruka Chino
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Project Researcher
Yutaro Hama
Profile
【学歴】
2015年 東海大学 工学部 生命化学科 卒業
2017年 東京大学 大学院医学系研究科 医科学専攻 修士課程 修了
2021年 東京大学 大学院医学系研究科 分子細胞生物学専攻 博士課程 修了
【職歴】
2018-2021年 日本学術振興会特別研究員DC1
2021年～ 東京大学 大学院医学系研究科 分子細胞生物学専攻 特任研究員
Results
The evolution of autophagy proteins - diversification in eukaryotes and potential ancestors in prokaryotes. Zhang S, Hama Y, Mizushima N. J Cell Sci . 2021 Jul 1;134(13):jcs233742. ZZ domains keep cytosol to vacuole delivery whiZZing along. Hama Y, Zhang S, Mizushima N. EMBO J. 2021 Jun 25;e108777. Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1. Okawa F*, Hama Y*, Zhang S*, Morishita H, Yamamoto H, Levine TP, Mizushima N. (* equally contributed) J Cell Sci. 2021 Mar 26:jcs.255877. SQSTM1L341V variant that is linked to sporadic ALS exhibits impaired association with MAP1LC3 in cultured cells. Nozaki M, Otomo A, Mitsui S, Ono S, Shirakawa R, Chen Y, Hama Y, Sato K, Chen X, Suzuki T, Shang HF, Hadano S. eNeurologicalSci. 2020 Nov 30;22:100301. TMEM41B functions with VMP1 in autophagosome formation. Morita K, Hama Y, Mizushima N. Autophagy 2019 May;15(5):922-923 Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation. Morita K, Hama Y, Izume T, Tamura N, Ueno T, Yamashita Y, Sakamaki Y, Mimura K, Morishita H, Shihoya W, Nureki O, Mano H, Mizushima N. J Cel Biol 2018, 217(11):3817-3828 A new probe to measure autophagic flux in vitro and in vivo. Morishita H, Kaizuka T, Hama Y, Mizushima N. Autophagy 2017, Apr 3;13(4):757-758. An Autophagic Flux Probe that Releases an Internal Control Kaizuka T*, Morishita H* (* equally contributed), Hama Y, Tsukamoto S, Matsui T, Toyota Y, Kodama A, Ishihara T, Mizushima T, Mizushima N. Mol. Cell 2016, Nov 17;64(4):835-849. Introductory Article
第29章 オートファジー関連薬剤 濱 祐太郎, 森下 英晃, 水島 昇. 決定版 阻害剤・活性化剤ハンドブック(羊土社). 2019 444-451. オートファジー活性の簡便かつ定量的な測定法 森下 英晃, 濱 祐太郎, 水島 昇. 実験医学, Vol.35 No.8 (5月号). 2017 1359-1365.
